Successful Tocilizumab Treatment for Scleritis
نویسندگان
چکیده
منابع مشابه
Successful Treatment of TAFRO Syndrome with Tocilizumab, Prednisone, and Cyclophosphamide
TAFRO syndrome is a rare systemic inflammatory disease characterized by thrombocytopenia, pleural effusion, fever, renal dysfunction, reticulin fibrosis of the bone marrow, and organomegaly. The clinical course varies significantly among patients. However, the prognosis is usually dismal in patients with severe TAFRO syndrome, and no optimal treatment has yet been established. We herein describ...
متن کاملSuccessful Tocilizumab Treatment in a Child With Refractory Takayasu Arteritis
Takayasu arteritis (TA) in the child remains a therapeutic challenge because corticosteroids and conventional immunosuppressive agents are not always safe or efficacious. The complex formed by interleukin6 (IL-6) and soluble IL-6 receptor appears to play a pivotal role in the pathogenesis of TA. We describe a favorable response to the anti-IL-6 receptor antibody tocilizumab (TCZ) in a child wit...
متن کاملSuccessful tocilizumab treatment in a child with refractory Takayasu arteritis.
Takayasu arteritis (TA) in the child remains a therapeutic challenge because corticosteroids and conventional immunosuppressive agents are not always safe or efficacious. The complex formed by interleukin-6 (IL-6) and soluble IL-6 receptor appears to play a pivotal role in the pathogenesis of TA. We describe a favorable response to the anti-IL-6 receptor antibody tocilizumab (TCZ) in a child wi...
متن کاملInfliximab for the treatment of refractory scleritis
BACKGROUND Scleritis is a potentially blinding inflammatory disorder. Standard care consists of systemic corticosteroids and immunosuppresants. The authors describe a series of 10 patients suffering from scleritis treated with the TNF inhibitor infliximab because this scleritis was refractory to standard therapy. METHODS The authors reviewed the medical records of patients with scleritis at the...
متن کاملSuccessful treatment of refractory anterior scleritis in primary Sjogren's syndrome with rituximab.
A nterior scleritis is an inflammation of the superficial, subconjunctival sclera which may follow infection or occur in rheumatic disease. Anterior scleritis due to secondary immune complex mediated vasculitis is an extremely rare extraglandular manifestation in primary Sjögren’s syndrome. Symptoms of anterior scleritis are pain, tearing, and photophobia. If left untreated, anterior scleritis ...
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ژورنال
عنوان ژورنال: Ocular Immunology and Inflammation
سال: 2019
ISSN: 0927-3948,1744-5078
DOI: 10.1080/09273948.2019.1617885